Bond Elut Plexa PAX is a polymer anion exchange product (PAX) that establishes performance standards for the purification and reproducibility of polar and non-polar acidic analytes. The existing polymer based anion exchange adsorbents have significant differences in ion exchange capacity between batches, resulting in non reproducibility of the methods and poor data quality. Plexa PAX filler adopts a patented functionalization process, which can achieve very high reproducibility of anion exchange capacity, thus having more stable performance throughout the entire compound research or method cycle.
suchThe SPE product of Plexa PAX polymer hybrid mode comes with a simple, single non-polar and polar acidic analyte extraction method, which can achieve excellent purification effects, even when processing complex matrix samples such as plasma, satisfactory results can be obtained. This optimized anion exchange method can obtain clean extracts, high recovery rates, and low RSD values, reducing method development time, sample duplication analysis, and overall cost of processing each sample.
Common matrix |
Main extraction mechanism |
Type of compound |
Plasma, urine, biological fluids, and water-soluble samples |
Strong anion exchange |
Acidic compounds, carboxylic acid metabolites of drugs, peptides, and amino acids |
Bond Elut Plexa PAX
Explanation |
Unit |
Part number |
Straight pipe column | ||
30 mg,1 mL |
100 per pack |
|
60 mg,1 mL |
100 per pack |
|
30 mg,3 mL |
50/pack |
|
60 mg,3 mL |
50/pack |
|
200 mg,6 mL |
30/pack |
|
500 mg,6 mL |
30/pack |
Bond Elut Plexa PAX 96 well plate
Explanation |
Unit |
10 mg |
30 mg |
1 mL circular hole plate |
1/Package |
A4967010 |
A4967030 |
2 mL square well plate |
1/Package |
A3967010 |
A3967030 |
Common methods for Bond Elut Plexa PAX
Sample: |
100 μ L human plasma |
Preprocessing: |
Using 2% NH4Dilute OH at a ratio of 1:3 |
Activation: |
1. 500 μ L methanol 2. 500 μ L H2O |
Cleaning: |
1. 500 μ L H2O 2. 500 μ L methanol |
Elution: |
500 μ L 5% formic acid: methanol |
The volumes listed are relative to Bond Elut 96 1 mL porous plate, part number: A4967010。 |